BactoInteractDB Bacterial–Host Molecular Interactions
and Pathogenic Mechanisms

BactoInteractDB

An integrated database of bacterial–host
molecular interactions and pathogenic mechanisms

BactoInteractDB curates experimentally validated and computationally predicted interactions between bacterial proteins and host molecules, linking virulence determinants to host targets, cellular pathways, phenotypes and disease outcomes.

Examples:Escherichia coliTLR4T3SSNF-κBStaphylococcus aureus
Illustration of a bacterial protein engaging a host target protein at the host cell membrane
214
Bacterial species
3,975
Bacteria–host interactions
2,980
Virulence factors
2,109
Host target proteins
1,881
Experimental structures
32
Literature sources

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Bacteria illustration

Bacteria

Browse bacterial species, strains, genomes and proteins.
Host Proteins illustration

Host Proteins

Explore host targets, functions and pathways.
Interactions illustration

Interactions

Search experimentally validated and predicted interactions.
Pathogenic Mechanisms illustration

Pathogenic Mechanisms

Discover affected pathways, cellular processes and phenotypes.
Structures illustration

Structures

View experimental 3D structures and interaction interfaces.